The recently completed clinical study evaluated the effectiveness of Urophenol®. This proprietary whole fruit cranberry extract features a high concentration of proanthocyanidins (PACs), versus typical cranberry supplements containing low PACs or non-standardized cranberry ingredients. PACs are chains of polymeric flavonoids which interact strongly with proteins and glycoproteins. They have been shown to suppress the adhesion of E.coli, the bacteria known to cause urinary tract infections.
The randomized, double-blind controlled study found that Urophenol® significantly reduces the number of symptomatic urinary tract infections (UTIs) and symptomatic UTI with pyuria in women with moderate UTI recurrence by 43% when compared to low PAC supplementation. It also demonstrated that the high level of PACs in Urophenol® contributed to its multi-level modes of action, from the gut to the urinary tract.
According to Nathalie Richer, Diana Foods’ Global Product Manager Health & Nutrition, “This study confirms that the high concentration of proanthocyanidins found in Urophenol® makes it an excellent choice for UTI health supplementation products. We consider it a game-changer in the cranberry extract market segment.”
Richer, together with Teresa Kilgore, Global Head of Health & Nutrition Marketing, will be sharing detailed clinical evidence during the upcoming Vitafoods Insights webinar. Innovation and marketing teams at dietary supplement manufacturing companies who attend will learn about the latest understandings of the mechanism of action of cranberry PACs and hear about key scientific considerations to support formulations targeting urinary health.
To register for the webinar, click here.